News & Topics

Apr 21, 2016

Contributing to early detection and treatment of kidney disease
New release of automatic urine analysis system with space-saving design

ARKRAY, Inc. shall release the compact automatic urine analysis system AUTION ELEVEN AE-4021 on Thursday April 21, 2016. The instrument shall support simple and fast testing in hospitals and clinics, and contribute to the early detection and treatment of kidney ailments such as diabetic nephropathy,*1 including Chronic Kidney Disease (CKD). *2

The AUTION ELEVEN AE-4021, which shall be released by ARKRAY, Inc. (hereafter 'ARKRAY'), has been added with new features that meet the needs of the testing front line, on top of the high basic performance of the existing model AUTION ELEVEN AE-4020.

By simply dipping the dedicated urine test strips (AUTION SCREEN and AUTION Sticks series) and setting them in the tray, a maximum of 12 items for qualitative urine testing*3 can be measured, including glucose, protein and bilirubin. Furthermore, the instrument incorporates a space-saving design, taking into account the work space in testing laboratories and rooms. Therefore it can be installed in any type of location.

The instrument also supports the instrument urine test strips Uriflet S 11UA (due for release in mid-May 2016) and not only is it possible to conduct the simultaneous measurement of 11 items for qualitative urine testing, but the urine albumin/creatinine ratio*4 and protein/creatinine ratio*5 can also be calculated. Through these features, screening tests can be conducted for ailments such as diabetic nephropathy, including Chronic Kidney Disease (CKD). As a result, the instrument can serve as a useful tool for the risk management of the onset of kidney failure.

Since successfully developing the world's first automated urine analysis system in 1972, ARKRAY has provided fully automated qualitative urine analyzers, urine test strips and test data management systems to the market for more than 40 years. Moving forward, ARKRAY shall continue to develop products with high added value in the urine testing field, and contribute to the improved efficiency of urine testing, in addition to the early detection and treatment of kidney disease.


(Left) Uriflet S 11UA   (Right) AUTION ELEVEN AE-4021

Special features

◯ Fast processing with 7 seconds per sample
The time required to process one sample is 7 seconds. With this fast processing it is possible to reduce the time spent on testing.

◯ Space-saving design
With a B4 sized space-saving design, the instrument can be installed anywhere.

◯ Pursuing ease of use
By pursuing ease of use, the instrument features an auto start function, which automatically commences measurement once the test strips are simply set in the tray, and a left & right placement function that allows for test strips to be set on either of the left and right sides.

◯ Possible to input turbidity
It is possible to input 'turbidity' which expresses the level of cloudiness in the urine. The instrument can be effectively used as a back-up for a fully automatic urine qualitative testing analyzer.


*1 Diabetic nephropathy
A microvascular complication that occurs when chronic hyperglycemia persists over time. Clinically proteinuria (microalbuminuria in the initial stage), renal dysfunction, high blood pressure and adema are exhibited, and ultimately results in kidney failure.

*2 Chronic Kidney Disease (CKD)
Refers to chronic kidney damage. CKD has a deep association with lifestyle-related diseases such as high blood pressure and diabetes, in addition to metabolic syndrome. As the kidneys continue to be subjected to worsening levels of impairment caused by CKD, various risks consequently occur. (From 'CKD Examination Guide 2012' and 'CKD Examination Guidelines Based on Evidence 2013' (Japanese Society of Nephrology))

*3 Qualitative urine testing
Urinalysis is divided into qualitative urine testing, which is conducted as a provisional examination using urine test strips, and urine sediment testing, which measures formed components in urine such as cells and bacteria. With qualitative urine testing conditions such as proteinuria, urinary sugar and occult blood are measured.

*4 Urine albumin/creatinine ratio (Alb/Cre ratio)
An indicator that employs the ratio of the microalbumin and creatinine concentrations in urine, which are simultaneously measured. It is used as an indicator for diabetic nephropathy.

*5 Urine protein/creatinine ratio (Pro/Cre ratio)
An indicator that employs the ratio of the protein and creatinine concentrations in urine, which are simultaneously measured. It is used as an indicator for kidney function.

Overview of AUTION ELEVEN AE-4021

Name Automatic urine analysis system AUTION ELEVEN AE-4021
Release date April 21, 2016 (Thu)
   Meas. target Urine
   Meas. items Glu (Glucose), Pro (Protein), Bil (Bilirubin), Uro (Urobilinogen), Ket (Ketones), pH, Nit (Nitrite), Bld (Occult blood), Leu (Leukocytes), SG, color tone, Alb (Albumin), Cre (Creatinine)
(Calculation items: Alb/Cre ratio, Pro/Cre ratio)
   Meas. wavelength Quad wavelength LED (430, 565, 635, 760nm)
   Meas. principle Dual wavelength reflectance method (one wavelength only for BLD)
   Test strip AUTION Sticks series
AUTION SCREEN Microalbumin / Creatinine
Uriflet S 11UA (Due for release in mid-May 2016)
   Reaction interval 60 secs
   Processing speed 514 tests / hour (Fastest: 7 sec interval)
   Data memory 520 tests
   Display Custom LCD
   Printer Thermal printer (58mm width)
   Operating conditions
   Meas. conditions
Temp: 10 to 30℃, humidity: 20 to 80% (no condensation)
Temp: 10 to 30℃, humidity: 20 to 80% (no condensation)
Through temperature correction
   Power supply AC100 - 240V adaptor
   Power consumption 45VA
   Outer dimensions 210(W) × 328(D) × 170(H) mm
   Weight 3.6kg

This product will only be sold in Japan.

Overview of Uriflet S 11UA

Name Instrument urine test strip 'Uriflet S 11UA'
Release date Scheduled for mid-May 2016
   Meas. target Urine
   Meas. items Glu, Pro, Bld, pH, Bil, Uro, Ket, Nit, Leu, Cre, Alb,
(Calculation items: Alb/Cre ratio, Pro/Cre ratio)
   Supported device AUTION MAX AX-4060,AUTION ELEVEN AE-4021
Packaging unit 100 per pack

Sales except Japan to be determined.

These product will be sold through ARKRAY Marketing, Inc.
ARKRAY Marketing Inc. is ARKRAY's marketing supervision entity for Japan.